Specific effects of antitumor active norspermidine on the structure and function of DNA

We compared the effects of trivalent polyamines, spermidine (SPD) and norspermidine (NSPD), a chemical homologue of SPD, on the structure of DNA and gene expression. The chemical structures of SPD and NSPD are different only with the number of methylene groups between amine groups, [N-3-N-4-N] and [...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishio, Takashi, Yoshikawa, Yuko, Shew, Chwen-Yang, Umezawa, Naoki, Higuchi, Tsunehiko, Yoshikawa, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802174/
https://www.ncbi.nlm.nih.gov/pubmed/31628357
http://dx.doi.org/10.1038/s41598-019-50943-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802174/
https://www.ncbi.nlm.nih.gov/pubmed/31628357
http://dx.doi.org/10.1038/s41598-019-50943-1

Ejemplares similares