The free energy landscape of retroviral integration

Retroviral integration, the process of covalently inserting viral DNA into the host genome, is a point of no return in the replication cycle. Yet, strand transfer is intrinsically iso-energetic and it is not clear how efficient integration can be achieved. Here we investigate the dynamics of strand...

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Detalles Bibliográficos
Autores principales: Vanderlinden, Willem, Brouns, Tine, Walker, Philipp U., Kolbeck, Pauline J., Milles, Lukas F., Ott, Wolfgang, Nickels, Philipp C., Debyser, Zeger, Lipfert, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802197/
https://www.ncbi.nlm.nih.gov/pubmed/31628321
http://dx.doi.org/10.1038/s41467-019-12649-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802197/
https://www.ncbi.nlm.nih.gov/pubmed/31628321
http://dx.doi.org/10.1038/s41467-019-12649-w

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