Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake

Cancer-derived small extracellular vesicles (sEVs) induce stromal cells to become permissive for tumor growth. However, it is unclear whether this induction solely occurs through transfer of vesicular cargo into recipient cells. Here we show that cancer-derived sEVs can stimulate endothelial cell mi...

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Detalles Bibliográficos
Autores principales: Ko, Song Yi, Lee, WonJae, Kenny, Hilary A., Dang, Long H., Ellis, Lee M., Jonasch, Eric, Lengyel, Ernst, Naora, Honami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802217/
https://www.ncbi.nlm.nih.gov/pubmed/31646189
http://dx.doi.org/10.1038/s42003-019-0609-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802217/
https://www.ncbi.nlm.nih.gov/pubmed/31646189
http://dx.doi.org/10.1038/s42003-019-0609-x

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