Cacna1b alternative splicing impacts excitatory neurotransmission and is linked to behavioral responses to aversive stimuli

Presynaptic Ca(V)2.2 channels control calcium entry that triggers neurotransmitter release at both central and peripheral synapses. The Cacna1b gene encodes the α1-pore forming subunit of Ca(V)2.2 channels. Distinct subsets of splice variants of Ca(V)2.2 derived from cell-specific alternative splici...

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Detalles Bibliográficos
Autores principales: Bunda, Alexandra, LaCarubba, Brianna, Bertolino, Melanie, Akiki, Marie, Bath, Kevin, Lopez-Soto, Javier, Lipscombe, Diane, Andrade, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802325/
https://www.ncbi.nlm.nih.gov/pubmed/31630675
http://dx.doi.org/10.1186/s13041-019-0500-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802325/
https://www.ncbi.nlm.nih.gov/pubmed/31630675
http://dx.doi.org/10.1186/s13041-019-0500-1

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