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Cacna1b alternative splicing impacts excitatory neurotransmission and is linked to behavioral responses to aversive stimuli
Presynaptic Ca(V)2.2 channels control calcium entry that triggers neurotransmitter release at both central and peripheral synapses. The Cacna1b gene encodes the α1-pore forming subunit of Ca(V)2.2 channels. Distinct subsets of splice variants of Ca(V)2.2 derived from cell-specific alternative splici...
Autores principales: | Bunda, Alexandra, LaCarubba, Brianna, Bertolino, Melanie, Akiki, Marie, Bath, Kevin, Lopez-Soto, Javier, Lipscombe, Diane, Andrade, Arturo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802325/ https://www.ncbi.nlm.nih.gov/pubmed/31630675 http://dx.doi.org/10.1186/s13041-019-0500-1 |
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