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Altered activity in the nucleus raphe magnus underlies cortical hyperexcitability and facilitates trigeminal nociception in a rat model of medication overuse headache

BACKGROUND: The pathogenesis of medication overuse headache (MOH) involves hyperexcitability of cortical and trigeminal neurons. Derangement of the brainstem modulating system, especially raphe nuclei may contribute to this hyperexcitability. The present study aimed to investigate the involvement of...

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Detalles Bibliográficos
Autores principales: Potewiratnanond, Prangtip, le Grand, Supang Maneesri, Srikiatkhachorn, Anan, Supronsinchai, Weera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802338/
https://www.ncbi.nlm.nih.gov/pubmed/31638891
http://dx.doi.org/10.1186/s12868-019-0536-2