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Altered activity in the nucleus raphe magnus underlies cortical hyperexcitability and facilitates trigeminal nociception in a rat model of medication overuse headache
BACKGROUND: The pathogenesis of medication overuse headache (MOH) involves hyperexcitability of cortical and trigeminal neurons. Derangement of the brainstem modulating system, especially raphe nuclei may contribute to this hyperexcitability. The present study aimed to investigate the involvement of...
Autores principales: | Potewiratnanond, Prangtip, le Grand, Supang Maneesri, Srikiatkhachorn, Anan, Supronsinchai, Weera |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802338/ https://www.ncbi.nlm.nih.gov/pubmed/31638891 http://dx.doi.org/10.1186/s12868-019-0536-2 |
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