E3 ubiquitin ligases LNX1 and LNX2 are major regulators of the presynaptic glycine transporter GlyT2

The neuronal glycine transporter GlyT2 is an essential regulator of glycinergic neurotransmission that recaptures glycine in presynaptic terminals to facilitate transmitter packaging in synaptic vesicles. Alterations in GlyT2 expression or activity result in lower cytosolic glycine levels, emptying...

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Detalles Bibliográficos
Autores principales: de la Rocha-Muñoz, A., Núñez, E., Arribas-González, E., López-Corcuera, B., Aragón, C., de Juan-Sanz, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802383/
https://www.ncbi.nlm.nih.gov/pubmed/31628376
http://dx.doi.org/10.1038/s41598-019-51301-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802383/
https://www.ncbi.nlm.nih.gov/pubmed/31628376
http://dx.doi.org/10.1038/s41598-019-51301-x

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