Piperlongumine, a Novel TrxR1 Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cells by ROS-Mediated ER Stress

Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third leading cause of cancer-related deaths globally. Despite advances in diagnosis and treatment, the incidence and mortality of HCC continue to rise. Piperlongumine (PL), an alkaloid isolated from the fruit of the long pepper,...

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Detalles Bibliográficos
Autores principales: Zhang, Qianqian, Chen, Weiqian, Lv, Xiuling, Weng, Qiaoyou, Chen, Minjiang, Cui, Ri, Liang, Guang, Ji, Jiansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802400/
https://www.ncbi.nlm.nih.gov/pubmed/31680962
http://dx.doi.org/10.3389/fphar.2019.01180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802400/
https://www.ncbi.nlm.nih.gov/pubmed/31680962
http://dx.doi.org/10.3389/fphar.2019.01180

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