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Human blastocyst outgrowths recapitulate primordial germ cell specification events

Our current knowledge of the mechanisms leading to human primordial germ cell (PGC) specification stems solely from differentiation experiments starting from human pluripotent stem cells. However, information regarding the origin of PGCs in vivo remains obscure. Here we apply an improved system for...

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Detalles Bibliográficos
Autores principales: Popovic, Mina, Bialecka, Monika, Gomes Fernandes, Maria, Taelman, Jasin, Van Der Jeught, Margot, De Sutter, Petra, Heindryckx, Björn, Chuva De Sousa Lopes, Susana M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802404/
https://www.ncbi.nlm.nih.gov/pubmed/31211841
http://dx.doi.org/10.1093/molehr/gaz035