Alloactivation of Naïve CD4(+)CD8(−)CD25(+)T Regulatory Cells: Expression of CD8α Identifies Potent Suppressor Cells That Can Promote Transplant Tolerance Induction

Therapy with alloantigen-specific CD4(+)CD25(+) T regulatory cells (Treg) for induction of transplant tolerance is desirable, as naïve thymic Treg (tTreg) are not alloantigen-specific and are weak suppressor cells. Naïve tTreg from DA rats cultured with fully allogeneic PVG stimulator cells in the p...

Descripción completa

Detalles Bibliográficos
Autores principales: Verma, Nirupama D., Robinson, Catherine M., Carter, Nicole, Wilcox, Paul, Tran, Giang T., Wang, Chaunmin, Sharland, Alexandra, Nomura, Masaru, Plain, Karren M., Bishop, G. Alexander, Hodgkinson, Suzanne J., Hall, Bruce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802415/
https://www.ncbi.nlm.nih.gov/pubmed/31681288
http://dx.doi.org/10.3389/fimmu.2019.02397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802415/
https://www.ncbi.nlm.nih.gov/pubmed/31681288
http://dx.doi.org/10.3389/fimmu.2019.02397

Ejemplares similares