Cargando…

Alloactivation of Naïve CD4(+)CD8(−)CD25(+)T Regulatory Cells: Expression of CD8α Identifies Potent Suppressor Cells That Can Promote Transplant Tolerance Induction

Therapy with alloantigen-specific CD4(+)CD25(+) T regulatory cells (Treg) for induction of transplant tolerance is desirable, as naïve thymic Treg (tTreg) are not alloantigen-specific and are weak suppressor cells. Naïve tTreg from DA rats cultured with fully allogeneic PVG stimulator cells in the p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Verma, Nirupama D., Robinson, Catherine M., Carter, Nicole, Wilcox, Paul, Tran, Giang T., Wang, Chaunmin, Sharland, Alexandra, Nomura, Masaru, Plain, Karren M., Bishop, G. Alexander, Hodgkinson, Suzanne J., Hall, Bruce M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802415/ https://www.ncbi.nlm.nih.gov/pubmed/31681288 http://dx.doi.org/10.3389/fimmu.2019.02397

Ejemplares similares

Changes in Reactivity In Vitro of CD4(+)CD25(+) and CD4(+)CD25(−) T Cell Subsets in Transplant Tolerance
por: Hall, Bruce M., et al.
Publicado: (2017)

Interleukin-12 (IL-12p70) Promotes Induction of Highly Potent Th1-Like CD4(+)CD25(+) T Regulatory Cells That Inhibit Allograft Rejection in Unmodified Recipients
por: Verma, Nirupama Darshan, et al.
Publicado: (2014)

The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells
Publicado: (1991)

Endothelial Cells Modify the Costimulatory Capacity of Transmigrating Leukocytes and Promote Cd28-Mediated Cd4(+) T Cell Alloactivation
por: Denton, Mark D., et al.
Publicado: (1999)

Interleukin-5 (IL-5) Therapy Prevents Allograft Rejection by Promoting CD4(+)CD25(+) Ts2 Regulatory Cells That Are Antigen-Specific and Express IL-5 Receptor
por: Hall, Bruce M., et al.
Publicado: (2021)

CD4/CD8 ratio and CD8 counts predict CD4 response in HIV-1-infected drug naive and in patients on cART
por: Sauter, Rafael, et al.
Publicado: (2016)

Interleukin-5 Mediates Parasite-Induced Protection against Experimental Autoimmune Encephalomyelitis: Association with Induction of Antigen-Specific CD4(+)CD25(+) T Regulatory Cells
por: Tran, Giang T., et al.
Publicado: (2017)

Multiple sclerosis patients have reduced resting and increased activated CD4(+)CD25(+)FOXP3(+)T regulatory cells
por: Verma, Nirupama D., et al.
Publicado: (2021)

CD45-mediated control of TCR tuning in naïve and memory CD8(+) T cells
por: Cho, Jae-Ho, et al.
Publicado: (2016)

Identification and Characterization of Circulating Naïve CD4+ and CD8+ T Cells Recognizing Nickel
por: Bechara, Rami, et al.
Publicado: (2019)

Do Natural T Regulatory Cells become Activated to Antigen Specific T Regulatory Cells in Transplantation and in Autoimmunity?
por: Hall, Bruce M., et al.
Publicado: (2013)

Regulation of CD4(+)CD8(−)CD25(+) and CD4(+)CD8(+)CD25(+) T cells by gut microbiota in chicken
por: Lee, In Kyu, et al.
Publicado: (2018)

Shaping Heterogeneity of Naive CD8(+) T Cell Pools
por: Lee, Sung-Woo, et al.
Publicado: (2023)

CD8(+) memory T-cell inflation renders compromised CD4(+) T-cell-dependent CD8(+) T-cell immunity via naïve T-cell anergy
por: Xu, Aizhang, et al.
Publicado: (2017)

Decreased Numbers of CD4(+) Naive and Effector Memory T Cells, and CD8(+) Naïve T Cells, are Associated with Trichloroethylene Exposure
por: Hosgood, H. Dean, et al.
Publicado: (2012)

CD8 is required during positive selection of CD4-/CD8+ T cells
Publicado: (1990)

Expression of naive/memory (CD45RA/CD45RO) markers by peripheral blood CD4(+) and CD8(+) T cells in children with asthma
por: Machura, Edyta, et al.
Publicado: (2008)

CD4(+)CD25(+) T regulatory cells in renal transplantation
por: Cheung, Jason, et al.
Publicado: (2022)

Vitamin D receptor expression controls proliferation of naïve CD8(+) T cells and development of CD8 mediated gastrointestinal inflammation
por: Chen, Jing, et al.
Publicado: (2014)

Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells
por: Berton, Roger R., et al.
Publicado: (2023)

Organ-dependent in vivo priming of naive CD4(+),but not CD8(+),T cells by plasmacytoid dendritic cells
por: Sapoznikov, Anita, et al.
Publicado: (2007)

Migratory Properties of Naive, Effector, and Memory Cd8(+) T Cells
por: Weninger, Wolfgang, et al.
Publicado: (2001)

Protocol to isolate and enrich mouse splenic naive CD4(+) T cells for in vitro CD4(+)CD8αα(+) cell induction
por: Harada, Yosuke, et al.
Publicado: (2022)

One naive T cell, multiple fates in CD8(+) T cell differentiation
por: Gerlach, Carmen, et al.
Publicado: (2010)

CD32 is enriched on CD4(dim)CD8(bright) T cells
por: Virdi, Amber K., et al.
Publicado: (2020)

Long terms trends in CD4(+) cell counts, CD8(+) cell counts, and the CD4(+) : CD8(+) ratio
por: Hughes, Rachael A., et al.
Publicado: (2018)

Chronic viral infections impinge on naive bystander CD8 T cells
por: Barnstorf, Isabel, et al.
Publicado: (2020)

Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells
por: Blattman, Joseph N., et al.
Publicado: (2002)

Molecular and Cellular Characterization of Human CD8 T Suppressor Cells
por: Xu, Zheng, et al.
Publicado: (2016)

Tumor-derived exosomes induce CD8(+) T cell suppressors
por: Maybruck, Brian T., et al.
Publicado: (2017)

Cd8(+) but Not Cd8(−) Dendritic Cells Cross-Prime Cytotoxic T Cells in Vivo
por: den Haan, Joke M.M., et al.
Publicado: (2000)

Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity
por: Shinoda, Koji, et al.
Publicado: (2023)

Myeloid-derived suppressor cells and the efficacy of CD8(+) T-cell immunotherapy
por: Lesokhin, Alexander M., et al.
Publicado: (2013)

CD28(−) and CD28(low)CD8(+) Regulatory T Cells: Of Mice and Men
por: Vuddamalay, Yirajen, et al.
Publicado: (2017)

Transcriptional signatures of Itk-deficient CD3(+), CD4(+ )and CD8(+ )T-cells
por: Blomberg, K Emelie M, et al.
Publicado: (2009)

Induction of memory-like CD8(+) T cells and CD4(+) T cells from human naive T cells in culture
por: Tokumoto, Yasuhito, et al.
Publicado: (2021)

Role of CD4(+)T, CD8(+)T Cells, and CD4(+)T/CD8(+)T Cell Ratio in Gastric Cancer and Its Clinical Significance
por: Han, Jingqi, et al.
Publicado: (2022)

Expression of intrahepatic CD3, CD4, and CD8 T cells in biliary atresia
por: Behairy, Behairy E., et al.
Publicado: (2017)

CD160 isoforms and regulation of CD4 and CD8 T-cell responses
por: El-Far, Mohamed, et al.
Publicado: (2014)

CD3(+)CD8(+)CD28(−) T Lymphocytes in Patients with Lupus Nephritis
por: Żabińska, Marcelina, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tvmfl41ia2onp5n3i13s6drdsg