Quantitative Proteomic and Network Analysis of Differentially Expressed Proteins in PBMC of Friedreich’s Ataxia (FRDA) Patients

Friedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disorder caused by an expanded (GAA) trinucleotide repeat in the FXN gene. The extended repeats expansion results in reduced transcription and, thereby, decreased expression of the mitochondrial protein, frataxin. Given the ongoi...

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Detalles Bibliográficos
Autores principales: Pathak, Deepti, Srivastava, Achal Kumar, Padma, M. V., Gulati, Sheffali, Rajeswari, Moganty R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802492/
https://www.ncbi.nlm.nih.gov/pubmed/31680804
http://dx.doi.org/10.3389/fnins.2019.01054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802492/
https://www.ncbi.nlm.nih.gov/pubmed/31680804
http://dx.doi.org/10.3389/fnins.2019.01054

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