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Long-term use of pitolisant to treat patients with narcolepsy: Harmony III Study

STUDY OBJECTIVES: To asses the long-term safety and efficacy of pitolisant, an histamine H3-receptor antagonist, on narcolepsy. METHODS: This open-label, single-arm, pragmatic study, recruited adult patients with narcolepsy and Epworth Sleepiness Scale (ESS) score ≥12. After a titration period, pati...

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Detalles Bibliográficos
Autores principales: Dauvilliers, Yves, Arnulf, Isabelle, Szakacs, Zoltan, Leu-Semenescu, Smaranda, Lecomte, Isabelle, Scart-Gres, Catherine, Lecomte, Jeanne-Marie, Schwartz, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802569/
https://www.ncbi.nlm.nih.gov/pubmed/31529094
http://dx.doi.org/10.1093/sleep/zsz174