MicroRNA-455-3p promotes TGF-β signaling and inhibits osteoarthritis development by directly targeting PAK2

MicroRNAs (miRNAs, miR) play a key role in the pathogenesis of osteoarthritis (OA). Few studies have examined the regulatory role of P21-activated kinases (PAKs), a family of serine/threonine kinases, in OA. The aim of this study was to determine whether miR-455-3p can regulate cartilage degeneratio...

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Detalles Bibliográficos
Autores principales: Hu, Shu, Zhao, Xiaoyi, Mao, Guping, Zhang, Ziji, Wen, Xingzhao, Zhang, Chengyun, Liao, Weiming, Zhang, Zhiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802609/
https://www.ncbi.nlm.nih.gov/pubmed/31586040
http://dx.doi.org/10.1038/s12276-019-0322-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802609/
https://www.ncbi.nlm.nih.gov/pubmed/31586040
http://dx.doi.org/10.1038/s12276-019-0322-3

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