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The inhibition of chloride intracellular channel 1 enhances Ca(2+) and reactive oxygen species signaling in A549 human lung cancer cells

Chloride intracellular channel 1 (CLIC1) is a promising therapeutic target in cancer due to its intrinsic characteristics; it is overexpressed in specific tumor types and its localization changes from cytosolic to surface membrane depending on activities and cell cycle progression. Ca(2+) and reacti...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Rin, Lee, Jong-Yoon, Kim, Hyun-Ji, Hahn, Myong-Joon, Kang, Jong-Sun, Cho, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802611/
https://www.ncbi.nlm.nih.gov/pubmed/31316050
http://dx.doi.org/10.1038/s12276-019-0279-2