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The inhibition of chloride intracellular channel 1 enhances Ca(2+) and reactive oxygen species signaling in A549 human lung cancer cells
Chloride intracellular channel 1 (CLIC1) is a promising therapeutic target in cancer due to its intrinsic characteristics; it is overexpressed in specific tumor types and its localization changes from cytosolic to surface membrane depending on activities and cell cycle progression. Ca(2+) and reacti...
Autores principales: | Lee, Jae-Rin, Lee, Jong-Yoon, Kim, Hyun-Ji, Hahn, Myong-Joon, Kang, Jong-Sun, Cho, Hana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802611/ https://www.ncbi.nlm.nih.gov/pubmed/31316050 http://dx.doi.org/10.1038/s12276-019-0279-2 |
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