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Inhibition of RIPK1-dependent regulated acinar cell necrosis provides protection against acute pancreatitis via the RIPK1/NF-κB/AQP8 pathway

Currently, preliminary results have confirmed the existence of receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain-like protein (MLKL)-dependent necroptosis of pancreatic acinar cells during early acute pancreatitis (AP), which might be a potential target for the effective...

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Detalles Bibliográficos
Autores principales: Duan, Peng-yu, Ma, Yuan, Li, Xi-na, Qu, Feng-zhi, Ji, Liang, Guo, Xiao-yu, Zhang, Wang-jun, Xiao, Fan, Li, Le, Hu, Ji-sheng, Sun, Bei, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802613/
https://www.ncbi.nlm.nih.gov/pubmed/31375658
http://dx.doi.org/10.1038/s12276-019-0278-3