Cargando…
Inhibition of RIPK1-dependent regulated acinar cell necrosis provides protection against acute pancreatitis via the RIPK1/NF-κB/AQP8 pathway
Currently, preliminary results have confirmed the existence of receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain-like protein (MLKL)-dependent necroptosis of pancreatic acinar cells during early acute pancreatitis (AP), which might be a potential target for the effective...
Autores principales: | Duan, Peng-yu, Ma, Yuan, Li, Xi-na, Qu, Feng-zhi, Ji, Liang, Guo, Xiao-yu, Zhang, Wang-jun, Xiao, Fan, Li, Le, Hu, Ji-sheng, Sun, Bei, Wang, Gang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802613/ https://www.ncbi.nlm.nih.gov/pubmed/31375658 http://dx.doi.org/10.1038/s12276-019-0278-3 |
Ejemplares similares
-
RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system
por: Li, Dianrong, et al.
Publicado: (2017) -
TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1
por: Moujalled, D M, et al.
Publicado: (2013) -
Execution of RIPK3-regulated necrosis
por: Cai, Zhenyu, et al.
Publicado: (2014) -
Parkin regulates NF-κB by mediating site-specific ubiquitination of RIPK1
por: Wang, Yu, et al.
Publicado: (2018) -
The Role of RIPK1 and RIPK3 in Cardiovascular Disease
por: DeRoo, Elise, et al.
Publicado: (2020)