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Soluble RAGE attenuates AngII-induced endothelial hyperpermeability by disrupting HMGB1-mediated crosstalk between AT1R and RAGE

Increased endothelial permeability, one of the earliest signs of endothelial dysfunction, is associated with the development of cardiovascular diseases such as hypertension and atherosclerosis. Recent studies suggest that the receptor for advanced glycation end products (RAGE) regulates endothelial...

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Detalles Bibliográficos
Autores principales: Jeong, Jisu, Lee, Jiye, Lim, Juyeon, Cho, Soyoung, An, Soyoung, Lee, Myungeun, Yoon, Nara, Seo, Miran, Lim, Soyeon, Park, Sungha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802637/
https://www.ncbi.nlm.nih.gov/pubmed/31562296
http://dx.doi.org/10.1038/s12276-019-0312-5