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Adaptor protein CrkII negatively regulates osteoblast differentiation and function through JNK phosphorylation
The adaptor protein CrkII is involved in several biological activities, including mitogenesis, phagocytosis, and cytoskeleton reorganization. Previously, we demonstrated that CrkII plays an important role in osteoclast differentiation and function through Rac1 activation both in vitro and in vivo. I...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802640/ https://www.ncbi.nlm.nih.gov/pubmed/31554784 http://dx.doi.org/10.1038/s12276-019-0314-3 |