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Adaptor protein CrkII negatively regulates osteoblast differentiation and function through JNK phosphorylation

The adaptor protein CrkII is involved in several biological activities, including mitogenesis, phagocytosis, and cytoskeleton reorganization. Previously, we demonstrated that CrkII plays an important role in osteoclast differentiation and function through Rac1 activation both in vitro and in vivo. I...

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Detalles Bibliográficos
Autores principales: Kim, Jung Ha, Kim, Kabsun, Kim, Inyoung, Seong, Semun, Nam, Kwang-Il, Kim, Kyung Keun, Kim, Nacksung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802640/
https://www.ncbi.nlm.nih.gov/pubmed/31554784
http://dx.doi.org/10.1038/s12276-019-0314-3