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The transcription factor NFIL3 controls regulatory T-cell function and stability

Regulatory T (Treg) cells are a CD4 T-cell subset with an important role in immune tolerance; however, the mechanisms underlying Treg cell differentiation and function are incompletely understood. Here, we show that NFIL3/E4BP4, a transcription factor, plays a key role in Treg cell differentiation a...

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Detalles Bibliográficos
Autores principales: Kim, Hyeong Su, Sohn, Hyogon, Jang, Sung Woong, Lee, Gap Ryol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802641/
https://www.ncbi.nlm.nih.gov/pubmed/31311918
http://dx.doi.org/10.1038/s12276-019-0280-9