The pore-forming subunit Kir6.1 of the K-ATP channel negatively regulates the NLRP3 inflammasome to control insulin resistance by interacting with NLRP3

Excessive activation of the NLRP3 inflammasome is a key component contributing to the pathogenesis of various inflammatory diseases. However, the molecular mechanisms underlying its activation and regulation remain poorly defined. The objective of this study was to explore the possible function of t...

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Detalles Bibliográficos
Autores principales: Du, Ren-Hong, Lu, Ming, Wang, Cong, Ding, Jian-Hua, Wu, Guangyu, Hu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802643/
https://www.ncbi.nlm.nih.gov/pubmed/31387986
http://dx.doi.org/10.1038/s12276-019-0291-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802643/
https://www.ncbi.nlm.nih.gov/pubmed/31387986
http://dx.doi.org/10.1038/s12276-019-0291-6

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