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Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats

Microbial metabolites have emerged as critical components that mediate the metabolic effects of the gut microbiota. Here, we show that indole-3-propionic acid (IPA), a tryptophan metabolite produced by gut bacteria, is a potent anti-non-alcoholic steatohepatitis (NASH) microbial metabolite. Here, we...

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Detalles Bibliográficos
Autores principales: Zhao, Ze-Hua, Xin, Feng-Zhi, Xue, Yaqian, Hu, Zhimin, Han, Yamei, Ma, Fengguang, Zhou, Da, Liu, Xiao-Lin, Cui, Aoyuan, Liu, Zhengshuai, Liu, Yuxiao, Gao, Jing, Pan, Qin, Li, Yu, Fan, Jian-Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802644/
https://www.ncbi.nlm.nih.gov/pubmed/31506421
http://dx.doi.org/10.1038/s12276-019-0304-5