The flagellin-TLR5-Nox4 axis promotes the migration of smooth muscle cells in atherosclerosis

We hypothesized that NADPH oxidase 4 (Nox4) is involved in the formation of neointimal atherosclerotic plaques through the migration of smooth muscle cells (SMCs) in response to flagellin. Here, we demonstrate that TLR5-mediated Nox4 activation regulates the migration of SMCs, leading to neointimal...

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Detalles Bibliográficos
Autores principales: Kim, Jinoh, Yoo, Jung-Yeon, Suh, Jung Min, Park, Sujin, Kang, Dongmin, Jo, Hanjoong, Bae, Yun Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802658/
https://www.ncbi.nlm.nih.gov/pubmed/31292433
http://dx.doi.org/10.1038/s12276-019-0275-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802658/
https://www.ncbi.nlm.nih.gov/pubmed/31292433
http://dx.doi.org/10.1038/s12276-019-0275-6

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