Cargando…
The flagellin-TLR5-Nox4 axis promotes the migration of smooth muscle cells in atherosclerosis
We hypothesized that NADPH oxidase 4 (Nox4) is involved in the formation of neointimal atherosclerotic plaques through the migration of smooth muscle cells (SMCs) in response to flagellin. Here, we demonstrate that TLR5-mediated Nox4 activation regulates the migration of SMCs, leading to neointimal...
Autores principales: | Kim, Jinoh, Yoo, Jung-Yeon, Suh, Jung Min, Park, Sujin, Kang, Dongmin, Jo, Hanjoong, Bae, Yun Soo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802658/ https://www.ncbi.nlm.nih.gov/pubmed/31292433 http://dx.doi.org/10.1038/s12276-019-0275-6 |
Ejemplares similares
-
Flagellin-induced NADPH oxidase 4 activation is involved in atherosclerosis
por: Kim, Jinoh, et al.
Publicado: (2016) -
Deletion of NoxO1 limits atherosclerosis development in female mice
por: Buchmann, Giulia K., et al.
Publicado: (2020) -
TLR4-NOX2 axis regulates the phagocytosis and killing of Mycobacterium tuberculosis by macrophages
por: Lv, Jingzhu, et al.
Publicado: (2017) -
Host species adaptation of TLR5 signalling and flagellin recognition
por: Tahoun, Amin, et al.
Publicado: (2017) -
Flagellin-dependent TLR5/caveolin-1 as a promising immune activator in immunosenescence
por: Lim, Jae Sung, et al.
Publicado: (2015)