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Particulate matter-induced senescence of skin keratinocytes involves oxidative stress-dependent epigenetic modifications

Ambient air particulate matter (PM) induces senescence in human skin cells. However, the underlying mechanisms remain largely unknown. We investigated how epigenetic regulatory mechanisms participate in cellular senescence induced by PM with a diameter <2.5 (PM(2.5)) in human keratinocytes and mo...

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Detalles Bibliográficos
Autores principales: Ryu, Yea Seong, Kang, Kyoung Ah, Piao, Mei Jing, Ahn, Mee Jung, Yi, Joo Mi, Bossis, Guillaume, Hyun, Young-Min, Park, Chang Ook, Hyun, Jin Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802667/
https://www.ncbi.nlm.nih.gov/pubmed/31551408
http://dx.doi.org/10.1038/s12276-019-0305-4