Acetate attenuates inflammasome activation through GPR43-mediated Ca(2+)-dependent NLRP3 ubiquitination

Acetate has been indicated to be elevated and to regulate inflammation in inflammatory and metabolic diseases. The inflammasome serves as a key component of immune homeostasis, and its dysregulation can lead to various inflammatory disorders. However, little is known about the effects of acetate on...

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Detalles Bibliográficos
Autores principales: Xu, Mengda, Jiang, Zhengyu, Wang, Changli, Li, Na, Bo, Lulong, Zha, Yanping, Bian, Jinjun, Zhang, Yan, Deng, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802670/
https://www.ncbi.nlm.nih.gov/pubmed/31337751
http://dx.doi.org/10.1038/s12276-019-0276-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802670/
https://www.ncbi.nlm.nih.gov/pubmed/31337751
http://dx.doi.org/10.1038/s12276-019-0276-5

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