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Sex-determining region Y (SRY) attributes to gender differences in RANKL expression and incidence of osteoporosis

Receptor activator of nuclear factor κB ligand (RANKL) plays a crucial role in bone metabolism. RANKL gene misregulation has been implicated in several bone and cancer diseases. Here, we aimed to identify novel transcription regulators of RANKL expression. We discovered that transcription factors, s...

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Detalles Bibliográficos
Autores principales: Kodrič, Klemen, Zupan, Janja, Kranjc, Tilen, Komadina, Radko, Mlakar, Vid, Marc, Janja, Lovšin, Nika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802671/
https://www.ncbi.nlm.nih.gov/pubmed/31409771
http://dx.doi.org/10.1038/s12276-019-0294-3