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Are neuroendocrine negative small cell lung cancer and large cell neuroendocrine carcinoma with WT RB1 two faces of the same entity?

Until recently, small cell lung cancer (SCLC) was described as SCLC and SCLC variant, based upon cellular morphology and loss of neuroendocrine markers in the SCLC variant. However, based on recent research advances, driven in part by the increase in comprehensive genomic data, it has become clear t...

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Detalles Bibliográficos
Autores principales: Sonkin, Dmitriy, Thomas, Anish, Teicher, Beverly A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802707/
https://www.ncbi.nlm.nih.gov/pubmed/31645891
http://dx.doi.org/10.2217/lmt-2019-0005