ROCK1 induces dopaminergic nerve cell apoptosis via the activation of Drp1-mediated aberrant mitochondrial fission in Parkinson’s disease

Dopamine deficiency is mainly caused by apoptosis of dopaminergic nerve cells in the substantia nigra of the midbrain and the striatum and is an important pathologic basis of Parkinson’s disease (PD). Recent research has shown that dynamin-related protein 1 (Drp1)-mediated aberrant mitochondrial fis...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Hu, Changpeng, Huang, Jingbin, Liu, Wuyi, Lai, Wenjing, Leng, Faning, Tang, Qin, Liu, Yali, Wang, Qing, Zhou, Min, Sheng, Fangfang, Li, Guobing, Zhang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802738/
https://www.ncbi.nlm.nih.gov/pubmed/31578315
http://dx.doi.org/10.1038/s12276-019-0318-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802738/
https://www.ncbi.nlm.nih.gov/pubmed/31578315
http://dx.doi.org/10.1038/s12276-019-0318-z

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