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Simultaneous cardiac and respiratory inhibition during seizure precedes death in the DBA/1 audiogenic mouse model of SUDEP

This study was designed to evaluate cardiac and respiratory dysfunction in a mouse model of sudden unexpected death in epilepsy i.e., SUDEP. We simultaneously monitored respiration via plethysmography and the electrocardiogram via telemetry before, during, and after an audiogenic seizure. DBA/1 mice...

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Detalles Bibliográficos
Autores principales: Schilling, William P., McGrath, Morgan K., Yang, Tianen, Glazebrook, Patricia A., Faingold, Carl L., Kunze, Diana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802840/
https://www.ncbi.nlm.nih.gov/pubmed/31634345
http://dx.doi.org/10.1371/journal.pone.0223468