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Bayesian multivariate reanalysis of large genetic studies identifies many new associations

Genome-wide association studies (GWAS) have now been conducted for hundreds of phenotypes of relevance to human health. Many such GWAS involve multiple closely-related phenotypes collected on the same samples. However, the vast majority of these GWAS have been analyzed using simple univariate analys...

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Detalles Bibliográficos
Autores principales: Turchin, Michael C., Stephens, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802844/
https://www.ncbi.nlm.nih.gov/pubmed/31596850
http://dx.doi.org/10.1371/journal.pgen.1008431