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Targeting SREBP1 chemosensitizes colorectal cancer cells to gemcitabine by caspase-7 upregulation

Biomarkers for predicting chemotherapy response are important for treatment of colorectal cancer (CRC) patients.SREBP1is involved in cancer cell chemoresistance, but the biological consequences of this activity in CRC are poorly understood. We set up biochemical and cell biology analyzes to analyze...

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Detalles Bibliográficos
Autores principales: Shen, Wenlong, Xu, Ting, Chen, Dong, Tan, Xiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802928/
https://www.ncbi.nlm.nih.gov/pubmed/31601152
http://dx.doi.org/10.1080/21655979.2019.1676485