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Anterograde trafficking signals in GABA(A) subunits are required for functional expression

Pentameric GABA(A) receptors are composed from 19 possible subunits. The GABA(A) β subunit is unique because the β(1) and β(3) subunits can assemble and traffic to the cell surface as homomers, whereas most of the other subunits, including β(2), are heteromers. The intracellular domain (ICD) of the...

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Detalles Bibliográficos
Autores principales: Nuwer, Jessica L., Fleck, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802930/
https://www.ncbi.nlm.nih.gov/pubmed/31610743
http://dx.doi.org/10.1080/19336950.2019.1676368