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Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress

The inner nuclear membrane (INM) is a subdomain of the endoplasmic reticulum (ER) that is gated by the nuclear pore complex. It is unknown whether proteins of the INM and ER are degraded through shared or distinct pathways in mammalian cells. We applied dynamic proteomics to profile protein half-liv...

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Detalles Bibliográficos
Autores principales: Buchwalter, Abigail, Schulte, Roberta, Tsai, Hsiao, Capitanio, Juliana, Hetzer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802967/
https://www.ncbi.nlm.nih.gov/pubmed/31599721
http://dx.doi.org/10.7554/eLife.49796