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Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress
The inner nuclear membrane (INM) is a subdomain of the endoplasmic reticulum (ER) that is gated by the nuclear pore complex. It is unknown whether proteins of the INM and ER are degraded through shared or distinct pathways in mammalian cells. We applied dynamic proteomics to profile protein half-liv...
Autores principales: | Buchwalter, Abigail, Schulte, Roberta, Tsai, Hsiao, Capitanio, Juliana, Hetzer, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802967/ https://www.ncbi.nlm.nih.gov/pubmed/31599721 http://dx.doi.org/10.7554/eLife.49796 |
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