Modified Vaccinia Virus Ankara Can Induce Optimal CD8(+) T Cell Responses to Directly Primed Antigens Depending on Vaccine Design

A variety of strains of vaccinia virus (VACV) have been used as recombinant vaccine vectors with the aim of inducing robust CD8(+) T cell immunity. While much of the pioneering work was done with virulent strains, such as Western Reserve (WR), attenuated strains such as modified vaccinia virus Ankar...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Yik Chun, Croft, Sarah, Smith, Stewart A., Lin, Leon C. W., Cukalac, Tania, La Gruta, Nicole L., Drexler, Ingo, Tscharke, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803277/
https://www.ncbi.nlm.nih.gov/pubmed/31375596
http://dx.doi.org/10.1128/JVI.01154-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803277/
https://www.ncbi.nlm.nih.gov/pubmed/31375596
http://dx.doi.org/10.1128/JVI.01154-19

Ejemplares similares