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Modified Vaccinia Virus Ankara Can Induce Optimal CD8(+) T Cell Responses to Directly Primed Antigens Depending on Vaccine Design

A variety of strains of vaccinia virus (VACV) have been used as recombinant vaccine vectors with the aim of inducing robust CD8(+) T cell immunity. While much of the pioneering work was done with virulent strains, such as Western Reserve (WR), attenuated strains such as modified vaccinia virus Ankar...

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Detalles Bibliográficos
Autores principales:	Wong, Yik Chun, Croft, Sarah, Smith, Stewart A., Lin, Leon C. W., Cukalac, Tania, La Gruta, Nicole L., Drexler, Ingo, Tscharke, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803277/ https://www.ncbi.nlm.nih.gov/pubmed/31375596 http://dx.doi.org/10.1128/JVI.01154-19

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