Local inhibition of rRNA transcription without nucleolar segregation after targeted ion irradiation of the nucleolus

Nucleoli have attracted interest for their role as cellular stress sensors and as potential targets for cancer treatment. The effect of DNA double-strand breaks (DSBs) in nucleoli on rRNA transcription and nucleolar organisation appears to depend on the agent used to introduce DSBs, DSB frequency an...

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Detalles Bibliográficos
Autores principales: Siebenwirth, Christian, Greubel, Christoph, Drexler, Guido A., Reindl, Judith, Walsh, Dietrich W. M., Schwarz, Benjamin, Sammer, Matthias, Baur, Iris, Pospiech, Helmut, Schmid, Thomas E., Dollinger, Günther, Friedl, Anna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803363/
https://www.ncbi.nlm.nih.gov/pubmed/31492757
http://dx.doi.org/10.1242/jcs.232181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803363/
https://www.ncbi.nlm.nih.gov/pubmed/31492757
http://dx.doi.org/10.1242/jcs.232181

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