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The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons

Global epigenetic reprogramming is vital to purge germ cell-specific epigenetic features to establish the totipotent state of the embryo. This process transpires to be carefully regulated and is not an undirected, radical erasure of parental epigenomes. The TRIM28 complex has been shown to be crucia...

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Detalles Bibliográficos
Autores principales: Seah, Michelle K. Y., Wang, Yaju, Goy, Pierre-Alexis, Loh, Hui Mun, Peh, Wen Jun, Low, Diana H. P., Han, Brenda Y., Wong, Esther, Leong, Ei Leen, Wolf, Gernot, Mzoughi, Slim, Wollmann, Heike, Macfarlan, Todd S., Guccione, Ernesto, Messerschmidt, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803371/
https://www.ncbi.nlm.nih.gov/pubmed/30846446
http://dx.doi.org/10.1242/dev.170266