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The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons
Global epigenetic reprogramming is vital to purge germ cell-specific epigenetic features to establish the totipotent state of the embryo. This process transpires to be carefully regulated and is not an undirected, radical erasure of parental epigenomes. The TRIM28 complex has been shown to be crucia...
Autores principales: | Seah, Michelle K. Y., Wang, Yaju, Goy, Pierre-Alexis, Loh, Hui Mun, Peh, Wen Jun, Low, Diana H. P., Han, Brenda Y., Wong, Esther, Leong, Ei Leen, Wolf, Gernot, Mzoughi, Slim, Wollmann, Heike, Macfarlan, Todd S., Guccione, Ernesto, Messerschmidt, Daniel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803371/ https://www.ncbi.nlm.nih.gov/pubmed/30846446 http://dx.doi.org/10.1242/dev.170266 |
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