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PRC2 functions in development and congenital disorders

Polycomb repressive complex 2 (PRC2) is a conserved chromatin regulator that is responsible for the methylation of histone H3 lysine 27 (H3K27). PRC2 is essential for normal development and its loss of function thus results in a range of developmental phenotypes. Here, we review the latest advances...

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Detalles Bibliográficos
Autores principales: Deevy, Orla, Bracken, Adrian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803372/
https://www.ncbi.nlm.nih.gov/pubmed/31575610
http://dx.doi.org/10.1242/dev.181354