N-Glycolylneuraminic Acid (Neu5Gc) Null Large Animals by Targeting the CMP-Neu5Gc Hydroxylase (CMAH)

The two major sialic acids described in mammalian cells are the N-glycolylneuraminic acid (Neu5Gc) and the N-acetylneuraminic acid (Neu5Ac). Neu5Gc synthesis starts from the N-acetylneuraminic acid (Neu5Ac) precursor modified by an hydroxylic group addition catalyzed by CMP-Neu5Ac hydroxylase enzyme...

Descripción completa

Detalles Bibliográficos
Autores principales: Perota, Andrea, Galli, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803385/
https://www.ncbi.nlm.nih.gov/pubmed/31681287
http://dx.doi.org/10.3389/fimmu.2019.02396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803385/
https://www.ncbi.nlm.nih.gov/pubmed/31681287
http://dx.doi.org/10.3389/fimmu.2019.02396

Ejemplares similares