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Investigation of Cervical Tumor Biopsies for Chromosomal Loss of Heterozygosity (LOH) and Microsatellite Instability (MSI) at the HLA II Locus in HIV-1/HPV Co-infected Women

Background: A subgroup of women who are co-infected with human immunodeficiency virus type 1 (HIV-1) and human papillomavirus (HPV) progress rapidly to cervical disease regardless of high CD4 counts. Chromosomal loss of heterozygosity (LOH) and microsatellite instability (MSI) are early frequent gen...

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Detalles Bibliográficos
Autores principales: Chambuso, Ramadhani, Kaambo, Evelyn, Denny, Lynette, Gray, Clive M., Williamson, Anna-Lise, Migdalska-Sęk, Monika, Agenbag, Gloudi, Rebello, George, Ramesar, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803484/
https://www.ncbi.nlm.nih.gov/pubmed/31681558
http://dx.doi.org/10.3389/fonc.2019.00951