Randomized Phase II Trial of Triapine-Cisplatin-Radiotherapy for Locally Advanced Stage Uterine Cervix or Vaginal Cancers

Uterine cervix or vaginal cancers have inherent overactivity of ribonucleotide reductase (RNR), making these cancers rational targets for therapy based on interruption of cisplatin-radiotherapy-induced DNA damage repair. We conducted a pilot, open-label randomized phase II trial to evaluate the effi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunos, Charles A., Andrews, Stephen J., Moore, Kathleen N., Chon, Hye Sook, Ivy, S. Percy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803528/
https://www.ncbi.nlm.nih.gov/pubmed/31681600
http://dx.doi.org/10.3389/fonc.2019.01067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803528/
https://www.ncbi.nlm.nih.gov/pubmed/31681600
http://dx.doi.org/10.3389/fonc.2019.01067

Ejemplares similares