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Randomized Phase II Trial of Triapine-Cisplatin-Radiotherapy for Locally Advanced Stage Uterine Cervix or Vaginal Cancers
Uterine cervix or vaginal cancers have inherent overactivity of ribonucleotide reductase (RNR), making these cancers rational targets for therapy based on interruption of cisplatin-radiotherapy-induced DNA damage repair. We conducted a pilot, open-label randomized phase II trial to evaluate the effi...
Autores principales: | Kunos, Charles A., Andrews, Stephen J., Moore, Kathleen N., Chon, Hye Sook, Ivy, S. Percy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803528/ https://www.ncbi.nlm.nih.gov/pubmed/31681600 http://dx.doi.org/10.3389/fonc.2019.01067 |
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