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Heterogeneity and Plasticity of Human Breast Cancer Cells in Response to Molecularly-Targeted Drugs

Non-responsive subpopulation of tumor cells, and acquired resistance in initially responsive cells are major challenges for cancer therapy with molecularly-targeted drugs. While point mutations are considered the major contributing factor to acquired resistance, in this study we explored the role of...

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Detalles Bibliográficos
Autores principales: Bousoik, Emira, Nabiee, Ramina, Amirrad, Farideh, Nichols, Ashley, Witt, Rebecca, Mahdipoor, Parvin, Montazeri Aliabadi, Hamidreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803545/
https://www.ncbi.nlm.nih.gov/pubmed/31681603
http://dx.doi.org/10.3389/fonc.2019.01070