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MLPA as a complementary tool for diagnosis of chromosome 21 aberrations in childhood BCP-ALL
Chromosome 21 abnormalities are the most frequent genetic findings in childhood B cell precursor acute lymphoblastic leukemia (BCP-ALL) cases. Majority of patients are effectively diagnosed with fluorescence in situ hybridization (FISH) and karyotyping; however, some cases may require additional too...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803575/ https://www.ncbi.nlm.nih.gov/pubmed/31456164 http://dx.doi.org/10.1007/s13353-019-00509-8 |