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DNA repair in cancer initiation, progression, and therapy—a double-edged sword
Genomic and mitochondrial DNA molecules are exposed continuously for a damaging activity of chemical, physical, and internal genotoxicants. When DNA repair machinery is not working efficiently, the generation of DNA lesions and mutations leads to carcinogenic transformation. The high number of mutat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803590/ https://www.ncbi.nlm.nih.gov/pubmed/31468363 http://dx.doi.org/10.1007/s13353-019-00516-9 |